[HTML][HTML] Oligonucleotide-recognizing topoisomerase inhibitors (OTIs): precision gene editors for neurodegenerative diseases?
… a camptothecin analog could give sequence specific DNA-… Although camptothecin-TFO
conjugates have been shown to … How many optimization cycles it would take to achieve such an …
conjugates have been shown to … How many optimization cycles it would take to achieve such an …
[HTML][HTML] Production, bioprocessing and antiproliferative activity of camptothecin from Aspergillus terreus, endophyte of Cinnamomum camphora: restoring their biosynthesis by …
A Eldeghidy, G Abdel-Fattah, ASA El-Sayed… - Microbial Cell …, 2023 - Springer
… affinity to inhibits the human Topoisomerase 1 activity (IC 50 … were further optimized by the
Central Composite Design (… at m/z 305 is produced by the cleavage of C 18 H 11 NO 4 . The …
Central Composite Design (… at m/z 305 is produced by the cleavage of C 18 H 11 NO 4 . The …
[HTML][HTML] Bifunctional Aptamer Drug Carrier Enabling Selective and Efficient Incorporation of an Approved Anticancer Drug Irinotecan to Fibrin Gels
H Fujita, Y Kataoka, M Kuwahara - Applied Sciences, 2020 - mdpi.com
… bApt to irinotecan, a camptothecin analog commonly used for … to type I topoisomerase and
inhibit recombination with DNA, … –antibody or aptamer–aptamer conjugate can attract T and …
inhibit recombination with DNA, … –antibody or aptamer–aptamer conjugate can attract T and …